omicverse.bulk2single.bulk2single_plot_correlation

omicverse.bulk2single.bulk2single_plot_correlation(single_data, generate_single_data, celltype_key, return_table=False, figsize=(6, 6), cmap='RdBu_r')[source]

Plot correlation matrix between reference and generated single-cell data.

Compares expression patterns of cell types between original single-cell reference and bulk2single generated data using marker gene correlations.

Parameters:

  • single_data (anndata.AnnData) – Original single-cell reference AnnData.

  • generate_single_data (anndata.AnnData) – Generated single-cell AnnData for comparison.

  • celltype_key (str) – Cell-type column used to group cells before correlation.

  • return_table (bool) – If True, return numeric correlation matrix instead of plotting.

  • figsize (tuple) – Figure size passed to matplotlib.

  • cmap (str) – Colormap used for heatmap rendering.

Returns:

Correlation matrix when return_table=True; otherwise figure and axes.

Return type:

numpy.ndarray or Tuple[matplotlib.figure.Figure,matplotlib.axes.Axes]