omicverse.pp.remove_cc_genes

omicverse.pp.remove_cc_genes(adata, organism='human', corr_threshold=0.1)[source]

Remove cell-cycle-correlated genes from highly_variable_features.

Parameters:

  • adata (anndata.AnnData) – AnnData object containing HVG annotations.

  • organism ({"human", "mouse"}, default="human") – Species used to load canonical cell-cycle signatures.

  • corr_threshold (float, default=0.1) – Absolute correlation cutoff. HVGs with maximal correlation to cell-cycle genes above this threshold are removed.

Returns:

Rewrites adata.var['highly_variable_features'] after filtering.

Return type:

None