omicverse.bulk.batch_correction¶

omicverse.bulk.batch_correction(adata, batch_key=None, key_added='batch_correction')[source]¶

Perform batch effect correction using ComBat algorithm.

Parameters:

adata (AnnData) – AnnData object containing expression data.
batch_key (default: None) – Key in adata.obs containing batch information.
key_added (str (default: 'batch_correction')) – Name for the corrected data layer. Default: ‘batch_correction’.

Returns:

The function modifies adata.layers[key_added] in place with batch-corrected expression data.

Return type:

None