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Research

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Highlighted

Open collaborative writing with Manubot
Open collaborative writing with Manubot
Daniel S. Himmelstein, Vincent Rubinetti, David R. Slochower, Dongbo Hu, Venkat S. Malladi, Casey S. Greene, Anthony Gitter
PLOS Computational Biology   ·   04 Dec 2020   ·   doi:10.1371/journal.pcbi.1007128
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All

2023

OmicVerse: A single pipeline for exploring the entire transcriptome universe
OmicVerse: A single pipeline for exploring the entire transcriptome universe
Zehua Zeng, Yuqing Ma, Lei Hu, Yuanyan Xiong, Hongwu Du
Cold Spring Harbor Laboratory   ·   08 Jun 2023   ·   doi:10.1101/2023.06.06.543913
Chromatin and Gene Regulatory Dynamics of Optic Nerve Invasion in Retinoblastoma at Single-Cell Resolution
Chromatin and Gene Regulatory Dynamics of Optic Nerve Invasion in Retinoblastoma at Single-Cell Resolution
Yihan Zhao, Peng Liu, Lei Hu, Mingxi Ke, Nan Min, Zehua Zeng, Hongwu Du
Cold Spring Harbor Laboratory   ·   12 May 2023   ·   doi:10.1101/2023.05.10.540147

2022

Regulatory factor identification for nodal genes in zebrafish by causal inference
Regulatory factor identification for nodal genes in zebrafish by causal inference
Cencan Xing, Zehua Zeng, Yaqi Li, Bo Gong, Weimin Shen, Roshan Shah, Lu Yan, Hongwu Du, Anming Meng
Frontiers in Cell and Developmental Biology   ·   20 Oct 2022   ·   doi:10.3389/fcell.2022.1047363
Identify the origin and end cells and infer the trajectory of cellular fate automatically
Identify the origin and end cells and infer the trajectory of cellular fate automatically
Zehua Zeng, Cencan Xing, Lei Hu, Shah Roshan, Yuanyan Xiong, Hongwu Du
Cold Spring Harbor Laboratory   ·   30 Sep 2022   ·   doi:10.1101/2022.09.28.510020
Multifunctional DNA Hydrogel Enhances Stemness of Adipose‐Derived Stem Cells to Activate Immune Pathways for Guidance Burn Wound Regeneration
Multifunctional DNA Hydrogel Enhances Stemness of Adipose‐Derived Stem Cells to Activate Immune Pathways for Guidance Burn Wound Regeneration
Liping Zhou, Zehua Zeng, Songyang Liu, Tiantian Min, Wenmin Zhang, Xiaochun Bian, Hongwu Du, Peixun Zhang, Yongqiang Wen
Advanced Functional Materials   ·   04 Sep 2022   ·   doi:10.1002/adfm.202207466
Stem cells from human exfoliated deciduous teeth affect mitochondria and reverse cognitive decline in a senescence-accelerated mouse prone 8 model
Stem cells from human exfoliated deciduous teeth affect mitochondria and reverse cognitive decline in a senescence-accelerated mouse prone 8 model
Wenhuan Guo, Zehua Zeng, Cencan Xing, Jinghui Zhang, Wangyu Bi, ..., Donghui Wang, Yingxian Li, Xiaoshuang Zhang, Yongzhong Bian, Hongwu Du
Cytotherapy   ·   01 Jan 2022   ·   doi:10.1016/j.jcyt.2021.07.018
Composition of intestinal flora affects the risk relationship between Alzheimer's disease/Parkinson's disease and cancer
Composition of intestinal flora affects the risk relationship between Alzheimer's disease/Parkinson's disease and cancer
Zhongci Hang, Tong Lei, Zehua Zeng, Shanglin Cai, Wangyu Bi, Hongwu Du
Biomedicine & Pharmacotherapy   ·   01 Jan 2022   ·   doi:10.1016/j.biopha.2021.112343

2020

Open collaborative writing with Manubot
Open collaborative writing with Manubot
Daniel S. Himmelstein, Vincent Rubinetti, David R. Slochower, Dongbo Hu, Venkat S. Malladi, Casey S. Greene, Anthony Gitter
PLOS Computational Biology   ·   04 Dec 2020   ·   doi:10.1371/journal.pcbi.1007128
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ERgene: Python library for screening endogenous reference genes
ERgene: Python library for screening endogenous reference genes
Zehua Zeng, Yuzhe Xiong, Wenhuan Guo, Hongwu Du
Scientific Reports   ·   29 Oct 2020   ·   doi:10.1038/s41598-020-75586-5
High-throughput screening suggests glutathione synthetase as an anti-tumor target of polydatin using human proteome chip
High-throughput screening suggests glutathione synthetase as an anti-tumor target of polydatin using human proteome chip
Peng Chen, Lei Wang, Shutao Sun, Qingbing Zhou, Zehua Zeng, Mingliang Hu, Muhammad Hussain, Cheng Lu, Hongwu Du
International Journal of Biological Macromolecules   ·   01 Oct 2020   ·   doi:10.1016/j.ijbiomac.2020.06.061
Establishment and validation of a drug-target microarray for SARS-CoV-2
Establishment and validation of a drug-target microarray for SARS-CoV-2
Peng Chen, Zehua Zeng, Hongwu Du
Biochemical and Biophysical Research Communications   ·   01 Sep 2020   ·   doi:10.1016/j.bbrc.2020.05.217
Predictions for the binding domain and potential new drug targets of 2019-nCoV
Predictions for the binding domain and potential new drug targets of 2019-nCoV
Zehua Zeng, Zhi Luo, Hongwu Du
Cold Spring Harbor Laboratory   ·   02 Mar 2020   ·   doi:10.1101/2020.02.26.961938
Constructing knowledge graphs and their biomedical applications
Constructing knowledge graphs and their biomedical applications
David N. Nicholson, Casey S. Greene
Computational and Structural Biotechnology Journal   ·   01 Jan 2020   ·   doi:10.1016/j.csbj.2020.05.017

2018

Sci-Hub provides access to nearly all scholarly literature
Sci-Hub provides access to nearly all scholarly literature
Daniel S Himmelstein, Ariel Rodriguez Romero, Jacob G Levernier, Thomas Anthony Munro, Stephen Reid McLaughlin, Bastian Greshake Tzovaras, Casey S Greene
eLife   ·   01 Mar 2018   ·   doi:10.7554/eLife.32822